Chemistry plays the most challenging role in modern scientific world. After a long cherished dream has become successful with the opening of Honours Course in Chemistry since 2008-2009 session. The nature of the material world is being understood based on the areas of Chemistry which are conventionally called Inorganic, Organic, Physical and Analytical. The Chemistry Department is one of the earliest Department to be established by the Santipur College and situated in the Science Block within the College Campus. It offers both General course and honours course (self-financing) programs leading to B.Sc degree of Kalyani University. The most healthy and vibrant cultural milieu provided by the faculty and staff of the Department of Chemistry enable our students at all levels to explore, discover and learn chemistry through class teaching and hands-on-experience. Moreover the students make extensive use of excellent Departmental library facility. The Department is being steadily developed with all instrumental facilities funded by UGC. On the eve of International year of Chemistry (YIC) 2011, a “Concept Test in Chemistry” organized by Association of Chemistry Teachers, India was held on 17th December 2011 in the Department of Chemistry, Santipur College. Many students from various Colleges appeared in that Test and scored good percentage and one of the student of this Department scored highest percentage within the University of Kalyani Zone. Honours and general students of this Department have well performance, many Honours students occupying first class and after passing from this Department they engaged for higher education in different parts of India and outside of India. Many Ex-students engaged as Teachers in Schools and other professions.